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Abstract
Introduction. Klinefelter syndrome is the commonest chromosomal cause of non-obstructive azoospermia. Despite reports that these men can have children using assisted reproduction techniques, it is not common practice in the Egypt to offer sperm retrieval to these men.
Design. Case report.
Setting. Private IVF center (EIFC-IVF) and a university hospital.
Patient. A 24-year-old woman and a 29-year-old man with non-mosaic Klinefelter syndrome.
Intervention. Testicular sperm extraction followed by intracytoplasmic sperm injection and embryo transfer (TESE-ICSI).
Results. Fifteen immotile sperms were found, five oocytes were injected, and three embryos were transferred. Now the pregnancy is progressing beyond 20 weeks.
Conclusion. Spermatozoa from a patient with non-mosaic Klinefelter syndrome retrieved through TESE can lead to pregnancy.
Keywords:
Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.