Two successful pregnancies in a patient with chemotherapy-induced ovarian failure while on hormone replacement therapy

Abstract

Chemotherapeutic agents administered for the treatment of malignancies can result in the incidence of premature ovarian failure (POF). Ovarian failure is reflected by elevated serum follicle-stimulating hormone (FSH) levels that may reach menopausal levels, at which the chances of a pregnancy are considered extremely rare. We report a case of a 26-year-old female who experienced two successful pregnancies, despite her diagnosis with chemotherapy-induced POF. This case suggests that patients who suffer from POF secondary to chemotherapy might still retain enough ovarian function with good quality oocytes that could support a healthy pregnancy.

Keywords::

• Chemotherapy
• premature ovarian failure
• pregnancy
• hormone replacement therapy

Declaration of interest: The authors report no declarations of interest.