The ultrasonographic detection of follicular rupture at the time of intrauterine insemination: is it really decisive?

Abstract

Our aim is to assess the impact of the ultrasonographic detection of follicular rupture on the intrauterine insemination success. A total of 313 women undergoing ovarian stimulation for intrauterine insemination were enrolled. Transvaginal ultrasonography was performed to check whether the dominant follicle had ruptured and according to that the patients were divided into two groups. The ultrasound detection of follicular rupture was observed in 156 patients (54%). The independent variables favoring follicular rupture were: Age (t: 7.646, p < 0.0005), FSH value (t: −5.637, p < 0.0005), duration of infertility (t: −4.265, p < 0.0005), menstrual cycle length (t: −4.927, p < 0.0005). Moreover, the logistic regression analysis demonstrated that the predictive variables for follicular rupture were: FSH value (OR 1.7, CI 95% 1.3–2.3, p < 0.0005), duration of infertility (OR 2.6, CI 95% 1.6–4.2, p < 0.0005) and menstrual cycle length (OR 2.4, CI 95% 1.7–3.4, p < 0.0005). Pregnancy occurred in 23 patients of the group A (14.7%) and in 22 patients of the group B (16.5%) without a significant difference (p = 0.6). The logistic regression analysis confirmed that neither the evidence of follicular rupture nor any other variables influenced the pregnancy rate.

Chinese abstract

我们的目的是评估超声探测下卵泡破裂对宫腔内人工授精成功的影响。总计313例因宫腔内人工授精进行卵巢刺激的妇女被纳入研究。通过阴道超声检查优势卵泡是否破裂，然后据此将患者分为两组。超声检查发现卵泡破裂的有156例（54％）。支持卵泡破裂的独立变量有：年龄(t: 7.646, p50.0005)，FSH值 (t: 􏰁5.637, p50.0005)，不孕的时间(t: 􏰁4.265, p50.0005),，月经周期长度(t: 􏰁4.927, p50.0005).。此外逻辑回归分析显示卵泡破裂的预测变量为：FSH 值(OR 1.7, CI 95% 1.3–2.3, p50.0005), 不孕时间 (OR 2.6, CI 95% 1.6–4.2, p50.0005) 和月经周期长度(OR 2.4, CI 95% 1.7–3.4, p50.0005)。A组出现23例患者妊娠（14.7%），B组有22例患者妊娠（16.5%），没有显著差异(p1⁄40.6)。逻辑回归分析证实既没有证据证明卵泡破裂或者其他变量影响妊娠率。

• Female infertility
• insemination
• ovarian follicle
• ovulation detection

Declaration of interest

The authors have no conflict of interest to declare.