Action of vasopressin in superfused human granulosa cells in vitro

T. Rabe Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany

A. Przylipiak Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany

H. Müller Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany

J. Przylipiak Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany

B. Runnebaum Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany

Abstract

Arginine-vasopressin as well as luteinizing hormone (LH)/follicle-stimulating hormone (FSH) stimulate progesterone release in superfused human granulosa cells. Extracellular administration of inositol trisphosphate (10₋₆ mol/l) or calcium ions (10₋₄ mol/l) mimics the action of both arginine-vasopressin and LH/FSH and evokes progesterone secretion in superfused granulosa cells.

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Action of vasopressin in superfused human granulosa cells in vitro

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Action of vasopressin in superfused human granulosa cells in vitro

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