![Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/5944/TOC-Subject-Sample-2021-Medicine-Dentistry-Nursing-Allied-Health.jpg"})
Abstract
Background: The intraovarian IGF-I system is now viewed as a potential regulator of ovarian function.
Methods: A thorough literature review of the English-speaking literature, special emphasis being placed on the hypothesis under study.
Results: Current data support the view that intraovarian IGF-I may act as an amplifier of gonadotropin hormonal action. The role of IGF-I as a determinant of follicular fate remains a matter of study.
Conclusions: The intraovarian IGF-I system is projected to play a central role in ovarian physiology by amplifying gonadotropin hormonal action and by possibly playing a role in determining follicular fate.