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Abstract
Much has been learned about the treatment of obsessive-compulsive disorders (OCD) in the last decade. Diagnostic criteria are now well-defined, adequate numbers of patients are currently available, and we now have an assessment instrument (the Yale-Brown Obsessive Compulsive Scale) that is sensitive to change and has demonstrated reliability and validity. We currently have medications that have been well-studied in adequately designed controlled trials that predictably help the majority of OCD patients. This paper will review the considerable data on the use of medications in patients with OCD. In addition, an approach to patients with resistant symptoms will be presented.