8
Views
1
CrossRef citations to date
0
Altmetric
Original Article

Biological markers of serotonin receptors in depression and animal models of depression

Pages 69-83 | Published online: 11 Jul 2009
 

Summary

The mechanism of action of antidepressant drugs is postulated to be linked in part to alterations which these drugs cause in the availability of serotonin, and in the sensitivity of serotonin receptors. Studying biological markers of serotonin receptors in animal models of depression as well as in patients with depression can expand our understanding of how antidepressants work. This article reviews the actions of various known antidepressants on serotonin systems in animal models of depression, and how these actions are linked to the therapeutic mechanism of antidepressants in patients with major depressive disorder.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.