Maternal dietary counseling during pregnancy and infant fatty acid profiles

Abstract

We aimed to explore whether maternal dietary counseling to increase the intake of unsaturated fatty acids (FA) is reflected in infant FA status. Serum cholesteryl ester (CE) and triacylglycerol (TAG) FA were analyzed from infants of 45 women randomized to receive dietary counseling from the first trimester of pregnancy and 45 control women. Counseling resulted in a higher intake of polyunsaturated FA and a lower intake of saturated FA. The dietary intake was reflected in cord blood TAGs: the n−6 to n−3 FA ratio was lower [mean difference −0.50 (95%CI −0.95 to −0.06)] and the sum of n−3 FA was higher in the intervention than in the control group [1.46 (0.44 to 2.48)% of total FA]. Reasons for the lack of changes in the cord blood CE fraction and FA fractions at 1-month remain unclear, but may indicate that the changes achieved in the maternal diet through counseling were too modest.

• Diet
• fetal blood
• polyunsaturated fatty acids
• pregnant women
• randomized controlled trial

Acknowledgements

We would like to thank Ulla-Maija Eriksson for her clinical work with the study participants and Patrick Gallagher for the grammatical review of the article. Provision of food products was by Raisio plc (Raisio, Finland).