Enantioselective Bioconversion of Non-Natural Compounds

Atsuo Tanaka Department of Synthetic Chemistry and Biological Chemistry, Faculty of Engineering, Kyoto University Yoshida, Sakyo-ku, Kyoto, 606-01, Japan

Toshiaki Fukui Department of Synthetic Chemistry and Biological Chemistry, Faculty of Engineering, Kyoto University Yoshida, Sakyo-ku, Kyoto, 606-01, Japan

Takuo Kawamoto Department of Synthetic Chemistry and Biological Chemistry, Faculty of Engineering, Kyoto University Yoshida, Sakyo-ku, Kyoto, 606-01, Japan

Abstract

Enantioselective bioconversion of organosilicon compounds was successfully carried out with hydrolases and a dehydrogenase. Substituents on silicon atom were found to affect the efficiency of the reactions. In many cases, the characteristics of silicon atom reflected the reactivity.

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Enantioselective Bioconversion of Non-Natural Compounds

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Enantioselective Bioconversion of Non-Natural Compounds

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