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Review Article

STb and AIDA-I: The missing link?

Pages 212-220 | Received 07 Apr 2009, Accepted 22 Feb 2010, Published online: 06 Apr 2010
 

Abstract

Escherichia coli enterotoxigenic strains produce one or more toxins which action result in production of diarrhea in animals including Man. One of these toxins, STb, has been mainly associated with colibacillosis in swine. Although highly prevalent in pigs with diarrhea, a relation between STb and disease was arduous to establish. With the recent recognition of a new adhesin, originally found in human E. coli isolates, named AIDA (adhesin involved in diffuse adherence) and its association with new E. coli pathotypes to which STb is linked, new light was shed on STb toxic potency. In this review, the association of STb and AIDA is examined according to the recent knowledge gained with newly described E. coli pathotypes.

Acknowledgements

The author thanks Jacinthe Lachance for the artwork.

Declaration of interest

J.D.D. is supported by grants from the Natural Sciences and Engineering Research Council of Canada (139070) and Fonds Québécois de la recherche sur la nature et les technologies (PR-114426). The author alone is responsible for the content and writing of the paper.

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