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Abstract
The first report of a halometabolite from a microorganism is that of Zopf1 who, in 1904, isolated diploicin from a lichen. Since that time, with few exceptions (some to be noted as this review continues), the field of microbial halogenation has been dominated by a chemotaxonomic philosophy; and a halobiochemical album has been slowly filled with neatly catalogued specimens.