Nucleotide sequence of ovine macrophage interleukin-1 beta cDNA

H-F. Seow CSIRO, Division of Animal Health, Animal Research Laboratory, Private Bag No. 1, Parkville, Victoria, 3052, Australia

J. S. Rothel CSIRO, Division of Animal Health, Animal Research Laboratory, Private Bag No. 1, Parkville, Victoria, 3052, Australia

M J. David CSIRO, Division of Animal Health, Animal Research Laboratory, Private Bag No. 1, Parkville, Victoria, 3052, Australia

P. R. Wood CSIRO, Division of Animal Health, Animal Research Laboratory, Private Bag No. 1, Parkville, Victoria, 3052, Australia

Abstract

We have cloned and sequenced the cDNA for the coding region of ovine alveolar macrophage interleukin-1β. At the nucleotide level, the ovine cDNA shares 95, 74 and 71 % homology with the bovine, human and murine cDNA equivalents or homologs. Comparison at the amino acid level revealed 95% homology with bovine IL-1β and approximately 57% with the human and murine homologs.

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Nucleotide sequence of ovine macrophage interleukin-1 beta cDNA

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Nucleotide sequence of ovine macrophage interleukin-1 beta cDNA

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