Sequence and expression of a Drosophila melanogaster cDNA encoding a putative ribosomal protein

Abstract

An abundant ovarian cDNA from Drosophila melanogaster has been cloned and sequenced. The predicted protein sequence is similar to that of the ribosomal protein 1024 of Dictyostelium discoideum, the 40S ribosomal protein ys11 of Saccharomyces cerevisiae and a 22 kd protein from Trypanosoma brucei. It seems, therefore, that the Drosophila cDNA also encodes a ribosomal protein. Transcripts are found at all stages of the life cycle but are especially abundant in the ovary, suggesting that this mRNA is maternally stored for utilization in embryogenesis to enable the rapid production of ribosomal proteins and assembly of ribosomes.

Key Words:

• ribosomal proteins
• maternal gene expression