Molecular cloning and sequence of bovine Msx-1 homeobox-containing gene cDNA from a bovine odontoblast library

Tadahiro Iimura Department of Biochemistry, Tokyo Medical and Dental University, Yushima, Bunkyo-Ku, Tokyo, Japan

Shinichiro Oida Department of Biochemistry, Tokyo Medical and Dental University, Yushima, Bunkyo-Ku, Tokyo, Japan

Kohsuke Takeda First Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tokyo Medical and Dental University, Yushima Bunkyo-Ku, Tokyo, Japan

Yutaka Maruoka Second Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tokyo Medical and Dental University, Yushima, Bunkyo-Ku, Tokyo, Japan

Hitoyata Shimokawa Department of Biochemistry, Tokyo Medical and Dental University, Yushima, Bunkyo-Ku, Tokyo, Japan

Kyomi Ibaraki Department of Biochemistry, Tokyo Medical and Dental University, Yushima, Bunkyo-Ku, Tokyo, Japan

Satoshi Sasaki Department of Biochemistry, Tokyo Medical and Dental University, Yushima, Bunkyo-Ku, Tokyo, Japan

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Abstract

Screening of a bovine odontoblast cDNA library from developing incisor with murine Msx-1 and Msx-2 cDNA probes led to the isolation of three positive clones. All of them encoded for a sequence of a protein containing 297 amino acids. The responsible gene was designated as bovine Msx-1 (bMsx-1) due to the high homology with the human MSX-1 and mouse Msx-1 sequences.

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Molecular cloning and sequence of bovine Msx-1 homeobox-containing gene cDNA from a bovine odontoblast library

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Molecular cloning and sequence of bovine Msx-1 homeobox-containing gene cDNA from a bovine odontoblast library

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