Abstract
A clone isolated from a mouse skeletal muscle cDNA library by differentially screening for sequences expressed in skeletal but not cardiac muscle was found to correspond to the a-isoform of casein kinase I. The bulk of the clone corresponded to the 3′-untranslated region of the mRNA, which is isoform-specific. Hybridization to mRNA indicated a tissue-specific distribution for this isoform of casein kinase I.
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