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Original Article

A Pseudoautosomal Boundary-Like Element Adjacent to the SSAVI Locus at 18q21

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Pages 115-119 | Received 24 Aug 1998, Published online: 11 Jul 2009
 

Abstract

Pseudoautosomal boundary-like (PABL) elements have been found at transition sites between genomic regions with different GC-contents. A new PAB related sequence was found immediately adjacent to the S71 provirus on human chromosome 18q21.1–2 (officially designated the SSAVZ locus). The S71 PABL element was full-length as defined by comparison with elements identified at the pseudoautosoma1 boundaries of the sex chromosomes and in the MHC region. The d'-ends of all PABL elements showed significant homology to functional CpG-islands, indicating that this similarity is a new common feature of PABL elements.

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