Trisomy 10 as the Sole Abnormality in Biphenotypic Leukemia

Tetsuya Inoue Department of Internal Medicine, Shiga University of Medical Science, Seta Tukinowa, Otsu, 520-2192, JAPANCorrespondence[email protected]

Yoshihide Fujiyama Department of Internal Medicine, Shiga University of Medical Science, Seta Tukinowa, Otsu, 520-2192, JAPAN

Shizuka Kitamura Department of Internal Medicine, Shiga University of Medical Science, Seta Tukinowa, Otsu, 520-2192, JAPAN

Akira Andoh Department of Internal Medicine, Shiga University of Medical Science, Seta Tukinowa, Otsu, 520-2192, JAPAN

Keiko Hodohara Department of Internal Medicine, Shiga University of Medical Science, Seta Tukinowa, Otsu, 520-2192, JAPAN

Tadao Bamba Department of Internal Medicine, Shiga University of Medical Science, Seta Tukinowa, Otsu, 520-2192, JAPAN

Abstract

We observed a case of acute biphenotypic leukemia with trisomy 10 as the sole abnormality. The patient was an adult male diagnosed with ALL(L2). Cell marker studies showed positivity for CD3, CD7, CD13 and CD33, so the phenotypic diagnosis was determined to be biphenotypic leukemia. No case of biphenotypic leukemia with trisomy 10 has been previously reported, until now.

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Trisomy 10 as the Sole Abnormality in Biphenotypic Leukemia

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Trisomy 10 as the Sole Abnormality in Biphenotypic Leukemia

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