Primary Effusion Lymphoma in an Hiv-Negative Patient with No Serologic Evidence of Kaposi's Sarcoma Virus

Jose Rodriguez Departments of Lymphoma/Myeloma and Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, and the Department of Pathology, University of California at Los Angeles, Los Angeles, California

Jorge E. Romaguera Departments of Lymphoma/Myeloma and Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, and the Department of Pathology, University of California at Los Angeles, Los Angeles, California

Ruth L. Katz Departments of Lymphoma/Myeloma and Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, and the Department of Pathology, University of California at Los Angeles, Los Angeles, California

Jonathan Said Departments of Lymphoma/Myeloma and Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, and the Department of Pathology, University of California at Los Angeles, Los Angeles, California

Fernando Cabanillas Departments of Lymphoma/Myeloma and Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, and the Department of Pathology, University of California at Los Angeles, Los Angeles, California

Abstract

Primary effusion lymphoma (PEL) is a newly described high-grade B cell lymphoma which develops in association with Kaposi's sarcoma-associated herpesvirus (KSV) in human immunodeficiency virus (HIV)-infected individuals. We hereby describe a very unusual presentation of PEL that developed in the abdominal cavity of an HIV negative, KSV negative patient with a 1-year history of refractory ascites due to alcohol-related liver cirrhosis. Possible factors aiding lymphomagenesis in the cirrhotic state are discussed.

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Primary Effusion Lymphoma in an Hiv-Negative Patient with No Serologic Evidence of Kaposi's Sarcoma Virus

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Primary Effusion Lymphoma in an Hiv-Negative Patient with No Serologic Evidence of Kaposi's Sarcoma Virus

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