Low-Grade Non-Hodgkin's Lymphoma in a Patient with Systemic Lupus Erythematosus

Tadeusz Robak Department of Hematology, Medical University of Łódz, Poland

Ewa Robak Department of Dermatology, Medical University of Łódz, Poland

Jacek Bartkowiak Department of Molecular Biology, Medical University of Łódz, Poland

Jerzy Z BłonSki Department of Hematology, Medical University of Łódz, Poland

Hanna Niewiadomska Department of Oncology, Medical University of Łódz, Poland

Ewa Wawrzyniak Department of Hematology, Medical University of Łódz, Poland

Abstract

Coexistence of systemic lupus erythematosus (SLE) with low-grade non-Hodgkin's lymphoma (LGNHL) has been described occasionally in the literature with the potential pathogenetic role of monoclonal B CD5+/CD19+ cells. We report a case of LGNHL which developed 18 months after diagnosis of SLE. The monoclonal population of lymphocytes in the peripheral blood and bone marrow was CD5/CD19 negative but CD19/CD22 positive. The SLE responded well to treatment with prednisone and the course of the LGNHL was stable and cytotoxic treatment was not required.

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Low-Grade Non-Hodgkin's Lymphoma in a Patient with Systemic Lupus Erythematosus

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Low-Grade Non-Hodgkin's Lymphoma in a Patient with Systemic Lupus Erythematosus

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