Acute Liver Failure as Initial Manifestation of Low-Grade Non-Hodgkin's Lymphoma Transformation into Large-Cell Lymphoma

Moshe Yeshurun Service des maladies du sang, Paris, France; The Institute of Hematology, The Chaim Cheba Medical Centre, Tel-Hashomer and Sackler School of Medicine, Tel-Aviv University, Israel

Francoise Isnard Service des maladies du sang, Paris, France

Laurent Garderet Service des maladies du sang, Paris, France

Jean Rambeloarisoa Service des maladies du sang, Paris, France

Sophie Prevot Service d'anatomie pathologique, Paris, France

Nicolas Carbonell Service d'hepatologie, hopital Saint-Antoine, Paris, France

Albert Najman Service des maladies du sang, Paris, France

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Abstract

Acute liver failure as an initial manifestation of primary non-Hodgkin's lymphoma is a rare phenomenon with a grim prognosis. We report for the first time on a patient with a history of follicular lymphoma in complete remission, presenting fulminant liver failure due to massive liver infiltration by transformed lymphoma cells and portal vein thrombosis, as an initial manifestation of transformation into large-cell lymphoma

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Acute Liver Failure as Initial Manifestation of Low-Grade Non-Hodgkin's Lymphoma Transformation into Large-Cell Lymphoma

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Acute Liver Failure as Initial Manifestation of Low-Grade Non-Hodgkin's Lymphoma Transformation into Large-Cell Lymphoma

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