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Original Article

Extramedullar Acute Myeloid Leukemia (Granulocytic Sarcoma) with Arm Paresis, Maculopapular Exanthema and Organ Involvement

, , , &
Pages 1619-1621 | Received 29 Jan 2003, Published online: 06 Apr 2010
 

Abstract

Granulocytic sarcoma (extramedullary myelosarcoma, chloroma) is a rare extramedullar myeloid tumor which can occur at any anatomical site as isolated finding or associated with acute myelogenous leukemia (AML) or myelodysplastic syndrome (MDS). In this case, we describe a 71-year-old man who presented with incomplete paresis of the left arm, periorbital swelling, a maculopapular exanthema and organ involvement including testis and stomach. The tumors responded to combination chemotherapy and the patient fully recovered. However, after five months the patient relapsed and died quickly. This case confirms the importance of including granulocytic sarcoma in the differential diagnoses of a variety of diseases. In AML, the presence of granulocytic sarcoma is associated with worse overall survival. When diagnosed, it should be treated with intensive chemotherapy as soon as possible.

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