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Abstract
The relative distribution of non-Hodgkin lymphoma (NHL) subtypes differs markedly around the world. The aim of this study was to report this distribution in Algeria. A panel of four hematopathologists classified 197 consecutive cases according to the World Health Organization classification, including 87.3% B-cell and 12.7% T- or natural killer (NK)-cell NHLs. This series was compared with similar cohorts from Western Europe (WEU) and North America (NA). Algeria had a significantly higher frequency of diffuse large B-cell lymphoma (DLBCL: 52.8%) and a lower frequency of follicular lymphoma (FL: 13.2%) compared with WEU (DLBCL: 32.2%; FL: 20.0%) and NA (DLBCL: 29.3%; FL: 33.6%). The frequency of mantle cell lymphoma was lower in Algeria (2.5%) compared with WEU (8.3%). Smaller differences were also found among the NK/T-cell lymphomas. In conclusion, we found important differences between Algeria and Western countries, and further epidemiologic studies are needed to explain these differences.
Acknowledgements
We thank all the haematologists and pathologists from Algeria who contributed to this study: K. Mekhelef, C. Aboura, L. Louanchi, M. Ramaoun, K. Bendissari, M. Belhani (Centre Hospitalier Universitarie Beni Messous, Algiers); H. Henneb, M. Allouda, H. Ait Ali (Centre Hospitalier Universitarie Tizi Ouzou, Algeria); N. Terki, N. Ait Amer, F. Tensaout, R. Hamladji (Centre Pierre Marie Curie, Algiers); H. Benmebarek, A. Abdennebi, L. Kalem (Centre Hospitalier Universitarie Parnet, Algiers); C. Graradj, Y. Lamouti (Centre Hospitalier Universitarie Blida, Algeria).
Potential conflict of interest:
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