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Diffuse large B-cell lymphoma cell-of-origin classification using the Lymph2Cx assay in the context of BCL2 and MYC expression status

Samantha KendrickDepartment of Pathology, University of Arizona, Tucson, AZ, USA,

Katalin TusDepartment of Pathology, University of Arizona, Tucson, AZ, USA,

George WrightNational Cancer Institute, Bethesda, MD, USA,

Elaine S. JaffeLaboratory of Pathology, National Cancer Institute, Bethesda, MD, USA,

Andreas RosenwaldInstitute of Pathology, University of Wuerzburg, and Comprehensive Cancer Center Mainfranken, Wuerzburg, Germany,

Elías CampoDepartment of Pathology, Hospital Clínic, Barcelona, Spain,

Wing Chung ChanDepartment of Pathology, City of Hope National Medical Center, Duarte, CA, USA,

Joseph M. ConnorsCentre for Lymphoid Cancer, British Columbia Cancer Agency, Vancouver, BC, Canada,

Rita M. BrazielDepartment of Clinical Pathology, Oregon Health & Science University, Portland, OR, USA,

German OttDepartment of Clinical Pathology, Robert-Bosch-Krankenhaus and Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany,

Jan DelabieDepartment of Pathology, Oslo University Hospital, Radiumhospitalet, Oslo, Norway,

James R. CookDepartment of Molecular Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH, USA,

Dennis D. WeisenburgerDepartment of Pathology, City of Hope National Medical Center, Duarte, CA, USA,

Timothy C. GreinerDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA,

Kai FuDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA,

Louis M. StaudtMetabolism Branch, Center for Cancer Research, National Cancer Institute, National Health Institutes, Bethesda, MD, USA, and

Randy D. GascoyneCentre for Lymphoid Cancer, British Columbia Cancer Agency, Vancouver, BC, Canada, ;Department of Pathology, British Columbia Cancer Agency, Vancouver, BC, Canada

David W. ScottCentre for Lymphoid Cancer, British Columbia Cancer Agency, Vancouver, BC, Canada,

Lisa M. RimszaDepartment of Pathology, University of Arizona, Tucson, AZ, USA, Correspondence[email protected]

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Potential conflict of interest:

This work was funded by the National Cancer Institute (1U01CA157581-01). S.K. is supported by a Lymphoma Research Foundation Post-Doctoral Fellowship.

Disclosure forms provided by the authors are available with the full text of this article at www.informahealthcare.com/lal.

Supplementary materials available on line Supplementary Fig.1 and 2

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Diffuse large B-cell lymphoma cell-of-origin classification using the Lymph2Cx assay in the context of BCL2 and MYC expression status

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Diffuse large B-cell lymphoma cell-of-origin classification using the Lymph2Cx assay in the context of BCL2 and MYC expression status

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