Histiocytosis Syndromes Classification, Diagnostic Features and Current Concepts

Abstract

The histiocytosis syndromes are broadly classified as those that feature dendritic cells and those that display only ordinary histiocytes in pathological lesions. The leukemias and lymphomas are malignant but the others defy simple assignment to basic pathological categorization. The ontogeny of histiocytes is considered, Langerhans cell histiocytosis and the hemophagocytic syndromes are discussed in detail and a conceptual context is presented

Key Words:

• Histiocytosis
• dendritic cells
• histiocytes
• Langerhans cells
• activation