Breakpoints of 11q25 in Three Similar Cases of B Non Hodgkin's Lymphoma

E. van den Berghe Center for Human Genetics, University of Leuven, Leuven, Belgium

C. Mecucci Center for Human Genetics, University of Leuven, Leuven, Belgium

J. Rodhain Department of Hematology, U.C.L., Brussels, Belgium

J. L. Michaux Department of Hematology, U.C.L., Brussels, Belgium

M. de Bruyere Department of Hematology, U.C.L., Brussels, Belgium

H. van den Berghe Center for Human Genetics, University of Leuven, Leuven, Belgium

Abstract

We report three cases of small B cell non Hodgkins lymphoma, two with plasmacytoid differentiation, presenting with a similar clinical picture and identical immunophenotype, who cytogenetically had breakpoints involving band 11q25. We suggest that this breakpoint may define a group of lymphomas closely related to the diffuse small cleaved cell lymphomas with t(11;14)(q13;q32).

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Breakpoints of 11q25 in Three Similar Cases of B Non Hodgkin's Lymphoma

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Breakpoints of 11q25 in Three Similar Cases of B Non Hodgkin's Lymphoma

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