Facial heliotrope rash as the initial manifestation of acute myelomonocytic leukemia

Vassiliki N. Tzavara Departments of Pathophysiology, National University of Athens, Laikon General Hospital, 75 Mikras Asias Street, 11527, Athens, Greece

Konstantinos Stamoulis Departments of Pathophysiology, National University of Athens, Laikon General Hospital, 75 Mikras Asias Street, 11527, Athens, Greece

Kyriaki G. Aroni Departments of Pathology, Medical School, National University of Athens, Laikon General Hospital, 75 Mikras Asias Street, 11527, Athens, Greece

Theodore Kordossis Departments of Pathophysiology, National University of Athens, Laikon General Hospital, 75 Mikras Asias Street, 11527, Athens, Greece

Kyriaki A. Boki Departments of Pathophysiology, National University of Athens, Laikon General Hospital, 75 Mikras Asias Street, 11527, Athens, Greece

Abstract

The association of leukocytoclastic vasculitis or dermatomyositis with malignancies has been reported. We describe a patient who developed a skin rash, histologically compatible with dermatomyositis, which during the course of the disease switched to leukocytoclastic vasculitis, which was accompanied with peripheral blood pancytopenia in the absence of any specific pathological manifestation from the bone marrow three years prior to the diagnosis of acute myelomonocytic leukemia (AMML).

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Facial heliotrope rash as the initial manifestation of acute myelomonocytic leukemia

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Facial heliotrope rash as the initial manifestation of acute myelomonocytic leukemia

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