Adverse Consequences of Chemical Immunomodulation

Abstract

Immunomodulating agents constitute a rapidly expanding group of biological substances with great therapeutic promises. However, any significant pharmacological advance is carrying its own potential for adverse consequences to human health, an issue of prime importance, particularly for the pharmaceutical industry in which operations are conducted in the face of national and international regulations increasingly committed to fighting drug-induced adverse reactions.

In the field of immunomodulation, exacerbation of the primary underlying disease, specific drug interactions and hypersensitivity reactions are the main complications deserving detailled investigation for the development of safer agents and adequate clinical practice.