19-Hydroxyandrostenedione - A Factor in Pregnancy Hypertension

Abstract

39 normotensive pregnant women (52 samples) and 47 patients with hypertensive disease of pregnancy (69 samples) between gestation 26 and 41 weeks were examined. The average plasma concentration of 19-hydroxyandrostenedione (19-OH-A) in the hypertensive pregnant women was significantly higher (p<t).001, mean ± standard deviation 482 ± 96.3 pg/ml) than that of the normotensive pregnant women (345 ± 60.2 pg/ml). 19-OH-A concentration was Independent of length of gestation in both normotensive or hypertensive pregnant women.