Noradrenaline and Dopamine in Fetal Compartment in Physiologic and Hypertensive Pregnancies

Abstract

In pregnancy induced hypertension an alteration in the function of sympathoadrenergic system occurs, whose role appears to be secondary in determining this pathology.

In view of this we have addressed our interest to the study of the two main vasoactive catecholamines noradrenaline and dopamine, in the fetal compartment of physiologic pregnancies with normal materno-feta I flows and pregnancies complicated by hypertension with altered flowmetric pattern. No significative difference between the main values of noradrenaline and dopamine in the two groups examined were found. Moreover in both groups the ratio noradrenaline: dopamine was unchanged.