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Abstract
Serum and urinary levels of magnesium, sodium, potassium and calcium were determined in normotensive pregnant women and in women with pregnancy-induced hypertension (PIH) during the second and third trimester. No significant differences were evident in serum total magnesium between the two groups over the two trimesters. Serum total calcium, however, was significantly lower during the third trimester in women with pregnancy-induced hypertension. The 24-hour urinalysis revealed significant hypomagnesuria and hypocalciuria in women with PIH. Serum and urinary levels of sodium and potassium were not significantly different between the two groups. These observations suggest a disturbance in magnesium and calcium metabolism in women with PIH. It is uncertain if this is a consequence of raised blood pressure or, as suggested by a number of other studies, a cause of the disorder.