24-Hour Urinary Creatinine Excretion is not Altered in Human Pregnancy

Abstract

Objective: To assess whether creatinine excretion alters in human pregnancy.

Methods: Longitudinal study of 24-h urinary excretion of creatinine during human pregnancy.

Main Outcome Measures: Relative creatinine excretion as pregnancy advanced.

Results: Twenty-four-hour creatinine excretion remained relatively constant as pregnancy advanced.

Conclusions: Creatinine excretion can be used with confidence during pregnancy for estimation of completeness of collection in examination of 24-h excretion of other metabolites.

We have shown that 24-h creatinine excretion is relatively constant during human pregnancy. Creatinine excretion can therefore be used with confidence during pregnancy for estimation of completeness of collection in examination of 24-h excretion of other metabolites.

Key Words:

• Human pregnancy
• Urinary creatinine