Obstructive sleep apnea syndrome and chronic kidney disease: a new cardiorenal risk factor

Abdullah OzkokDivision of Nephrology, Department of Internal Medicine

Asiye KanbayDepartment of Pulmonary Medicine, Istanbul Medeniyet University School of Medicine IstanbulTurkey

Ali Riza OdabasDivision of Nephrology, Department of Internal Medicine

Adrian CovicNephrology Clinic, Dialysis and Renal Transplant Center, ‘C.I. PARHON’ University Hospital, ‘Gr. T. Popa’ University of Medicine and Pharmacy IasiRomania

Mehmet KanbayDivision of Nephrology, Department of Internal MedicineCorrespondence[email protected]

Abstract

Clinical and experimental studies revealed that sleep apnea might be an insidious risk factor for the progression of kidney disease and development of cardiovascular events by exacerbating well-known risk factors, namely hypertension, type 2 diabetes mellitus and obesity. Furthermore, sleep apnea also has a negative impact on endothelial function. Therefore, sleep apnea might be defined as a new cardiorenal risk factor. In this review, we aimed to summarize the evidences supporting the complex inter-relations between sleep apnea and development and progression of chronic kidney disease.

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Obstructive sleep apnea syndrome and chronic kidney disease: a new cardiorenal risk factor

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Obstructive sleep apnea syndrome and chronic kidney disease: a new cardiorenal risk factor

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