Pre- and Postsynaptic Features of the Central Angiotensin Systems. Indications for A Role of Angiotensin Peptides in Volume Transmission and for Interactions with Central Monoamine Neurons

K. Fuxe Department of Histology and Neurobiology, Karolinska Institutet, Stockholm, Sweden

B. Bunnemann Department of Histology and Neurobiology, Karolinska Institutet, Stockholm, Sweden

M. Aronsson Department of Histology and Neurobiology, Karolinska Institutet, Stockholm, Sweden

B. Tinner Department of Histology and Neurobiology, Karolinska Institutet, Stockholm, Sweden

A. Cintra Department of Histology and Neurobiology, Karolinska Institutet, Stockholm, Sweden

G. von Euler Department of Histology and Neurobiology, Karolinska Institutet, Stockholm, Sweden

L. F. Agnati Department of Human Physiology, University of Modena, Italy

S. Nakanishi Department of Immunology, Faculty of Medicine, Kyoto University, Kyoto, Japan

H. Ohkubo Department of Immunology, Faculty of Medicine, Kyoto University, Kyoto, Japan

D. Ganten Department of Pharmacology, University of Heidelberg, Heidelberg, West-Germany

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Abstract

The transmitter receptor matches and mismatches in the angiotensin (ANG) immunoreactive (IR) neuronal systems of the rat CNS have been characterized in various regions by means of ANG II immunocyto-chemistry and ¹²⁵I-angiotensin II receptor autoradiography. By means of in situ hybridization the distribution of angiotensinogen mRNA has been mapped out and related to the distribution of ANG IR.

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Pre- and Postsynaptic Features of the Central Angiotensin Systems. Indications for A Role of Angiotensin Peptides in Volume Transmission and for Interactions with Central Monoamine Neurons

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Pre- and Postsynaptic Features of the Central Angiotensin Systems. Indications for A Role of Angiotensin Peptides in Volume Transmission and for Interactions with Central Monoamine Neurons

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