Oxidative Damage to Human Plasma Proteins by Ozone

Carroll E. Cross Department of Medicine, 4301 X Street, (Room 2120), University of California, Davis Medical Center, Sacramento, CA, 95817, USA

Abraham Z. Reznick Membrane Bioenergetics Group, University of California, Berkeley, CA, 94720, USA; Department of Morphological Sciences, Faculty of Medicine and Rappaport, Institute for Medical Research, Technion, Haifa, Israel

Lester Packer Membrane Bioenergetics Group, University of California, Berkeley, CA, 94720, USA

Paul A. Davts Department of Medicine, 4301 X Street, (Room 2120), University of California, Davis Medical Center, Sacramento, CA, 95817, USA

Yuichiro J. Suzuki Membrane Bioenergetics Group, University of California, Berkeley, CA, 94720, USA

Barry Halliwell Department of Medicine, 4301 X Street, (Room 2120), University of California, Davis Medical Center, Sacramento, CA, 95817, USA

Abstract

Exposure of human plasma to ozone produces oxidative protein damage, measured as protein carbonyl formation. Isolated human albumin or creatine phosphokinase are oxidized much faster than are total proteins. Consideration must be given to proteins as targets of oxidative injury by ozone in vivo.

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Oxidative Damage to Human Plasma Proteins by Ozone

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Oxidative Damage to Human Plasma Proteins by Ozone

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