Ph-Responsive Swelling Behavior of Collagen Complex Materials

Qiqing Zhang Tianjin University, Chinese Academy of Medical Sciences & Peking Union Medical College, P.O. Box, 25(204), Tianjin, P R China

Lingrong Liu Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, P.O. Box, 25(204), Tianjin, P R China

Haiying Zhou Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, P.O. Box, 25(204), Tianjin, P R China

Xiaoyu Wu Laboratory of Controlled Drug Delivery, Faculty of Pharmacy, University of Toronto, 19 Russell Street, Toronto, ON, M5S 2S2, Canada

K. D. Yao Tianjin University, Chinese Academy of Medical Sciences & Peking Union Medical College, P.O. Box, 25(204), Tianjin, P R China

Abstract

This article deals with an natural collagen blended with chitosan, poly(vinyl alcohol)(PVA). We investigated the swelling properties of collagen and collagen complex in the solution with different pH, and the swelling/deswelling behavior of collagen and collagen-chitosan complex when changing the pH of the medium from 5.4 to 1.8 and in the reverse. The results show that the swelling degree of collagen and collagen complex are dependent to pH of the solution, and the swelling behavior of collagen and collagen-chitosan complex are pH-responsive.

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Ph-Responsive Swelling Behavior of Collagen Complex Materials

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Ph-Responsive Swelling Behavior of Collagen Complex Materials

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