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Abstract
Twenty rabbits were used in a study conducted to determine the soft tissue biocompatibility of vitreous carbon micro-balloons and spheres. Histologic observations were made at designated intervals of 24 hr; 4, 7, and 15 days; and 1, 2, 4, 6, and 8 months.
The tissues were stained with hemotoxylin and eosin for microscopic observations. The findings showed that the implant material provoked minimal acute and chronic inflammatory response, which indicates that vitreous carbon is biocompatible and may serve as a soft tissue replacement material.
No indication of the rejection phenomena was observed during the entire period of this implant study.