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Original Article

The Effects of Polymer-Solvent Compositions in the Formation of Collodion Membrane Artificial Cells

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Pages 273-281 | Published online: 11 Jul 2009
 

Abstract

This study is an attempt to analyze the various polymer-solvent compositions for preparing collodion membrane artificial cells for biomedical applications. Cellulose nitrate was dissolved in different mixtures of alcohol-ether solutions and used for microencapsulation. The most optimal solvent solution consisted of 4 g% cellulose nitrate in 17.5% (volume) alcohol and 82.5% (volume) ether. The urease microcapsules prepared this way showed no leakage of enzyme under test conditions. Having established the optimal polymer-solvent compositions, an easier and more reproducible procedure has been established for preparing collodion membrane artificial cells.

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