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Biomaterials, Artificial Cells and Artificial Organs Volume 18, 1990 - Issue 5
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Original Article

Induction of Leukotriene B. Formation by Uialyzer Membranes

H. Schiffl Medizinische Klinik Innenstadt der Universität München, Zienssenstraße 1, 8000, München 2, FRG
&
Th. Strasser Medizinische Klinik Innenstadt der Universität München, Zienssenstraße 1, 8000, München 2, FRG
Pages 585-590 | Published online: 11 Jul 2009
 
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Abstract

Interactions between blood and dialysis membranes lead to activation of the 5-lipoxygenase pathway of the arachiodonic acid metabolism during hemodialysis. Newly generated leukotriene B4 (LIB4) may contribute to the multifaceted granulocyte abnormalities of uremic patients.

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