Diffuse Optics Determination of Hemoglobin Derivatives in Red Blood Cells and Liposome Encapsulated Hemoglobin

Abstract

High resolution optical absorption spectra of hemoglobin derivatives in red blood cells and phosphatidylcholine lipsomes were calculated from diffuse reflection and transmission spectra by means of the one-dimensional diffusion approximation. The numerical technique of singlular value decomposition was used to calculate the composition of red cell and liposome mixtures.