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Review Article

Role of miR-107 and its signaling pathways in diseases

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Pages 338-341 | Received 22 Jan 2014, Accepted 17 Feb 2014, Published online: 06 Mar 2014
 

Abstract

MicroRNAs exert their biologic effects by targeting specific mRNAs for degradation or translational inhibition. MicroRNA-mediated regulation is complex, potentially affecting expression of the host gene, related enzymes within the same pathway or apparently distinct targets. miR-107 is found to be implicated in the pathogenesis of some diseases. This review was performed to sum up the role of miR-107 and its signaling pathways in renal diseases.

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