Opiate Receptor Sites in the Rabbit Cerebellum: Autoradiographic Distribution

Abstract

The distribution of the [³H] diprenorphine binding sites in the rabbit cerebellum has been analyzed after specific labelling of tissue slices in vitro followed by autoradiohraphic processing. High, moderate and very low silver grain densities were observed over the molecular, granular and white layers, respectively. Within each layer, the distribution of the autoradiographic grain exhibited no evident patterning. Therefore, further work using complementary techniques is needed to determine the precise location of the opiate receptor sites in the rabbit cerebellum.