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Original Article

Vascularised Knee Joint Transplantation in Man: the First Two Years Experience

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Pages 320-327 | Received 01 Sep 2001, Published online: 04 Dec 2011
 

Abstract

Objective: To describe our early experience with a new technique for restoring destroyed knee joints to give reasonable functional results.

Design: Observational clinical trial.

Setting: Level-1-Trauma centre, Germany.

Subjects: 5 patients with large bone defects of the knee and loss of the extensor apparatus caused either by serious injury alone, or infection after serious injury.

Interventions: Transplantation of fresh and perfused knee joints with a vascular pedicle from multiorgan donors under immunosuppression.

Main outcome and measures: Ability to walk, need to remove one transplanted joint.

Results: Four patients are able to walk, the range of movement being from 50°-120°. The first patient additionally had to be provided with a total knee joint arthroplasty. In the third patient the graft became infected and had to be removed. She finally had an arthrodesis and bone lengthening by the Ilizarov technique.

Conclusions: Transplantation of the knee joint may be an alternative to bone lengthening or amputation for patients with total loss of the extensor apparatus.

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