Current role of ischemia-modified albumin in routine clinical practice

Abstract

Background: Ischemia-modified albumin has been proposed as a useful rule-out marker for the diagnosis of acute coronary syndrome in the emergency department.

Objective: To perform a review of ischemia-modified albumin use in the clinical practice.

Methods: We performed a comprehensive literature search by using electronic bibliographic databases.

Conclusion: Although the main limitation of ischemia-modified albumin at present is its low specificity, it may be a useful test to rule out acute coronary syndrome from low to moderate pre-test probability conditions with negative cardiac troponins and a negative ECG.

Keywords::

• Acute coronary syndrome
• chest pain
• acute myocardial ischemia
• Emergency department