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Original Article

Chemokines and ocular pathology caused by corneal infection with herpes simplex virus

, &
Pages 42-47 | Received 09 Jul 1998, Accepted 27 Aug 1998, Published online: 10 Jul 2009
 

Abstract

that continues to uncover new players. In this report we discuss the likely role of selected chemokines in the disease herpetic stromal keratitis (HSK). This lesion occurs as a sequel to herpes simplex virus infection and is currently accepted as an immunopathological process which primarily involves CD4+ T lymphocytes. In this review we discuss the events involved in HSK, the chemokine profile associated with this disease, and speculate on cellular activities and molecular events which characterize HSK as an immunopathological disease.

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