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Original Article

Influence of Dietary Supplementation with Fish on Plasma Total Cholesterol and Lipoprotein Cholesterol Fractions in Patients with Coronary Heart Disease

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Pages 107-115 | Published online: 13 Jul 2009
 

Abstract

The effects of dietary intake of fish on plasma cholesterol, triglycerides and lipoproteins were assessed in 30 patients diagnosed with coronary heart disease (myocardial infarction or angina pectoris). Biochemical determinations were performed while the subjects consumed their habitual diet (DI)' after eight weeks on a unified diet (D2), and after four weeks on a diet rich in jkh fat (D3), the fish diet significantly increased high density lipoprotein cholesterol (from 28.3± 1.0 mg dl−1 to 35.1± 1.4 mg dl−1 with diets D2 and D3 respectively, p < 0–001), significantly reduced low density lipoprotein cholesterol (from 172.9 ± 6.3 mg dl-1to 158.0 ±5.2 mg dl-1with diets D2 and D3 respectively (p < 0.001), and had no significant effect on plasma triglycerides or total cholesterol. the findings suggest that increasing dietary fih can significantly modify high and low density liprotein cholesterol, which are beneficial in preventing and treating coronary heart disease.

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