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International Journal of Psychiatry in Clinical Practice Volume 2, 1998 - Issue 3
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Original Article

Abnormal patterns of cerebral glucose metabolism in a pair of monozygotic twins with recent onset schizophrenia

F Ortun¯o Department of Psychiatry, University of Navarra, Spain
,
J Arbizu Department of Nuclear Medicine, University Hospital, University of Navarra, Spain
&
S Cervera Department of Psychiatry, University of Navarra, Spain
Pages 221-224 | Received 27 Oct 1997, Accepted 27 Apr 1998, Published online: 12 Jul 2009
 
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Abstract

An F-18-FDG-PET study of a pair of monozygotic twins with recent-onset schizophrenia revealed a higher index of metabolic asymmetry (IA) in the medial and posterior thalamus in both cases. Some questions regarding the influence of neuroleptic treatment and handedness on metablic patterns and the role of the thalamus in schizophrenia are discussed in the light of recent studies.

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