Modification du système de défense antiradicalaire de l'organisme sous l'influence de I'administration d'un facteur leucocytaire chez le lapin. Ses rapports avec l'accroissement de la radiorésistance par les biostimulants

Abstract

Injection in the rabbit of the leucocyte endogenous mediator (LEM) liberated by activated granulocytes provokes after 24 h an increase in the glutathione concentration, particularly in the spleen and in the kidney, as well as an increase in acute phase proteins and modifications of the zinc concentration in the plasma, the liver and the kidney. These modifications are compared with those provoked by non specific biostimulants which increase the radioresistance during periods varying from several days to several weeks. It may be that LEM or a component accompanying it in the injected fraction is a factor intervening in the increase in radioresistance caused by biostimulants.