Abstract
The authors investigated eight cases of aniridia by high resolution G-banding analysis (750 bands). A deletion of the short arm of chromosome 11 was found in two cases. One of these involved a three months old boy who was suspected of having Wilms' tumor. After elaborate Investigatións by pediatric surgeons, Wilms' tumor was found in his left kidney and was successfully removed in its early stage. These results suggest that high resolution G-banding analysis should be performed in all cases of infantile aniridia as a screening test for early detection of Wilms' tumor.