Screening for Antifungal Activity of Panamanian Plants

L. Rahalison Institut de Pharmacognosie et Phytochimie, Ecole de Pharmacie, Université de Lausanne, B.E.P., CH-1015, Lausanne, Switzerland

M. Hamburger Institut de Pharmacognosie et Phytochimie, Ecole de Pharmacie, Université de Lausanne, B.E.P., CH-1015, Lausanne, Switzerland

K. Hostettmann Institut de Pharmacognosie et Phytochimie, Ecole de Pharmacie, Université de Lausanne, B.E.P., CH-1015, Lausanne, Switzerland

M. Monod Laboratoire de Mycologie, Service de Dermatologie, Centre Hospitalier Universitaire Vaudois (C.H.U.V.), CH-1011, Lausanne, Switzerland

E. Frenk Laboratoire de Mycologie, Service de Dermatologie, Centre Hospitalier Universitaire Vaudois (C.H.U.V.), CH-1011, Lausanne, Switzerland

M. P. Gupta School of Pharmacy, University of Panama, Apartado 10767, Estafeta Universitaria, Panama, R of Panama

A. I. Santana School of Pharmacy, University of Panama, Apartado 10767, Estafeta Universitaria, Panama, R of Panama

M.D. Correa Herbarium of the University of Panama Smithsonian Tropical Research Institute, Panama

A. G. Gonzalez Instituto Universitario de Bioorganica “Antonio Gonzàlez”, Universidad de la Laguna, Tenerife, Spain

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Abstract

Crude extracts of Panamian plants (153 representing 28 species from 21 families) have been screened for antifungal activity against Candida albicans and Cladosporium cucumerinum. Activity was assessed in a semiquantitative fashion by bioautography on TLC plates. When tested at 100 μg, 15% of the extracts showed activity against one of the fungi, and 9% of the extracts were active against both test organisms. The most promising extracts originate from plants used in traditional medicine, such as Bursera simaruba (Burseraceae), Gliricidia sepium (Leguminosae) and Piper auritum (Piperaceae).

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Screening for Antifungal Activity of Panamanian Plants

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Screening for Antifungal Activity of Panamanian Plants

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