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Research Article

Screening of Tropical Medicinal Plants for Molluscicidal, Larvicidal, Fungicidal and Cytotoxic Activities and Brine Shrimp Toxicity

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Pages 294-307 | Accepted 11 Jun 1993, Published online: 27 Sep 2008
 

Abstract

Crude Extracts Of 36 Medicinal Plants Collected In Africa and South America Were Tested For Their Molluscicidal (Biomphalaria Glabrata), Larvicidal (Aedes Aegypti), Fungicidal (Cladosporium Cu-Cumerinum) and Cytotoxic (Against 2 Human Colon Carcinoma Cell Lines) Activities, As Well As For Brine Shrimp Toxicity (Artemia Salina). Members Of The Annonaceae, Guttiferae and Leguminosae Are Shown To Contain Compounds Highly Active In These 5 Bioassays. Three Of The Species Tested Stand Out For Their Marked Activity In Only One Bioassay: Rogeria Adenophylla and Sesamum Indicum (Pe-Daliaceae) Demonstrate Potent Larvicidal Activity and Adenium Obesum (Apocynaceae) Exhibits Very Strong Cytotoxicity.

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